Terpin Hydrate is a naturally derived expectorant formulated from turpentine, thyme, oregano, and other oils. Known for its mucus-loosening properties, it helps relieve congestion in acute and chronic bronchitis, pneumonia, and related pulmonary conditions.
Although no longer widely marketed as an OTC drug, Terpin Hydrate remains available in prescription-based compounded formulations. It enhances productive coughing and supports airway clearance, especially when paired with antitussives like codeine. Its natural origin and therapeutic effects make it a trusted ingredient in traditional and integrative respiratory care formulations.
Recognised for its expectorant action, Terpin Hydrate continues to be used in pharmacy-compounded syrups, elixirs, and natural cough formulations. It bridges botanical wellness and therapeutic efficacy for respiratory health.
PRODUCT NAME | TERPIN HYDRATE |
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MOL. FORMULA | C10H20O2.H2O |
MOL. WEIGHT | 190.28 |
CAS NO. | 2451-01-6 |
HSN-CODE | 2902 |
S.NO | TEST | SPECIFICATION |
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1 | APPEARANCE | A white powder ,odour slightly aromatic but not terebinthinate (no odour of turpentine oil ) |
2 | Identification | a. When heated at 1000C, terpin is formed which sublimes as fine needles. b. The liquid becomes turbid (cloudy) and acquires an odour of lilac (Hyacinth), due to the formation of terpineol. c. The principal spot in the sample chromatogram is similar in position, colour and size to the principal spot obtained in the reference chromatogram. d. IR complies with standard. |
3 | Acidity or Alkalinity | a. A 1% w/v solution in hot water is netural to litmus solution. b. NMT 0.2ml 0.02N HCL or NaOH is required to change the indicator. |
4 | Melting Range | 116°C to 119°C |
5 | Appearance of solution | Solution is clear and colorless. |
6 | Sulphated Ash | Not More Than 0.1% |
7 | Water | Between 9.0% to 10.0% |
8 | Related Substances | Any Spot in the chromatogram obtained with the test solution apart from the principle spot is not more intense than the principle spot in the chromatograph obtained with reference solution b. |
9 | Terpin Hydrate | 98.5% to 100.5% |
Terpin Hydrate is a terpene-derived crystalline compound widely known for its expectorant properties. Sourced from essential oils such as turpentine, thyme, and oregano, it facilitates the breakdown and expulsion of mucus from the respiratory tract. Historically used in mainstream respiratory medications, it is now primarily offered through compounding pharmacies for personalised respiratory care solutions.
In therapeutic practice, Terpin Hydrate is commonly blended with antitussives like codeine to manage both dry and productive coughs. By thinning mucus and easing its removal, it supports patients suffering from bronchitis, pneumonia, asthma, COPD, and other upper respiratory tract infections. Its role in enhancing airway clarity without suppressing the body’s natural defence mechanisms makes it a valuable agent in respiratory formulations.
Though withdrawn from general OTC availability in some markets due to regulatory shifts, Terpin Hydrate has retained clinical interest for its efficacy in compounded medications. It is still prescribed in specific regions and continues to serve in natural cough formulations, herbal elixirs, and wellness-based respiratory therapies.
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